[maxfieldj1]

Oh. Why then did Kelvin's estimates of 20 million years not kill the theory?

This is a dumb question. You might as well ask why we have airplanes despite Kelvin's claim that heavier than air flight is impossible. Just because a respected scientist says something doesn't mean that all other scientists are going to accept it as dogma.

Is it possible to demonstrate all mutations? I don't know. I'm giving examples of ways to falsify the theory, I never said it would be an easy task.

Also, in theory, this wouldn't falsify evolution. 'Harmful' isn't an empirical measure. Yes it is. If a mutation prevents an organism from reproducing then the mutation is harmful. There are other definitions you can apply that would also allow for an empirical measure of whether a mutation is harmful.