The research about MSM seems to show it's very hepful for joints, and also for arthritis. I've also seen a lot of times that the MSM is combined with glucosamin and chondroitin, which is also really helpful for joints. Actually, when I was purchasing it at Whole Foods the lady helping me automatically assumed I was getting it for my knee joints, and recomended the blend that has the glucosamin because they work very well off each other. I ended up with just the powder as I'm really just taking it for my skin, but from what I've read it's a good companion with gluc/chond for joints.