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Depends on a number of things.

The individual dogs, the area they are being left alone in, the exercise they've received prior and how long.

Roxy and Hades were left alone together many times. The dh and I's jobs at the time allowed us to be home most of the time, and if one of us wasn't home, it was only for a span of 2-3 three hours. If it was anymore, we took the dogs to my parents, usually because we didn't know how long we were actually going to be.

We set the video camera up a few times, Hades went right to bed, and Roxy lied down, patrolled, and intermittently freaked out at things outside. Sometimes Hades would come to look out the window to see what was going on, but then he would retreat back to his bed.

I think any breed of dog can get into fights with one another, but I personally do not believe it's necessary, for all dogs to be separated when unsupervised. If you're at all worried about your dogs getting into a scuffle over a toy while your gone, well then they probably should, but there are plenty of multi dog homes out there, probably the number being greater then the other, that leave dogs unsupervised with no issues. The stories you do hear of are likely people that disregarded signs of individual dogs in whatever breed that shouldn't be left alone unsupervised, dogs aren't exercised enough or are left alone too long.