Sister, we can shake hands of the people of the same gender and hug them. We can hug and shake hands of close relatives of the opposite gender aunt/uncle, son/daughter, brother/sister, etc. However Muslims are generally not allowed to freely interact with anyone of the opposite gender, including talking frankly, laughing, joking and flirting. You can shake hands with a Muslim woman. But even a Muslim woman cannot shake hands with a Muslim male.