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Nerotransmitters
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03-27-2012, 10:27 AM
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emupsMaispubs
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Oct 2005
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Nerotransmitters
http://en.wikipedia.org/wiki/Melatonin
In mammals, melatonin is biosynthesized in four enzymatic steps from the essential dietary amino acid
tryptophan
, with
serotonin
produced at the second step. Melatonin is secreted into the blood by the
pineal gland
in the brain. Known as the "hormone of darkness", it is secreted in darkness in both day-active (
diurnal
) and night-active (
nocturnal
) animals.
[18]
It may also be produced by a variety of peripheral cells such as
bone marrow cells
,
[19]
[20]
lymphocytes, and
epithelial cells
. Usually, the melatonin concentration in these cells is much higher than that found in the blood, but it does not seem to be regulated by the photoperiod.
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