I do not see speculation as a toxic drug unless it is really debasing you. I have speculated on philosophy and religion for many decades and have cetainly felt frustrated. On the credit side I cannot see my self locking into any ism. That said I find Buddhism quite nice, in the main........
The Atthakavagga belongs to the core teachings of the historical Buddha. I would recommend for gerrardthor to start there before moving to complex material such as the work of Nagarjuna. http://www.accesstoinsight.org/tipit...x.html#vagga-4
Gerrardthor - let's consider my below question carefully. You are suffered from concepts, or you are suffered from your desire to escape from concepts (and such desire is not fulfilled)? Buddhism does not teach to escape, but teach to be courageous to understand and deal with sufferings wisely.
I think Buddhism is a set of concepts that helps you understand the reality, so you no longer need to speculate.