Another complex aspect of this issue that needs to be investigated is the nature of mind, its relation to the physical constituents, and the state of mind ( located at the heart, traditionally, for Buddhists ) in the case of organ transplants. What psychological adjustments or temperament changes are entailed when another person's organ is transplanted into one's own body ? These important bio-ethical questions need to be looked at from various religious and cultural perspectives, as well as the physiological and economic.