avappyboalt |
09-13-2011 03:50 PM |
Leptin is a hormone that was discovered in 1994. It is produced by adipose tissue (fat) and tells the brain to shut off hunger and burn excess energy (instead of storing it as fat). The hormone affects other hormones, muscles, brain, etc... One theory is that obese persons have developed a leptin resistance where the brain cannot "hear" the signals from the hormone. The Leptin Reset prescription was developed by Dr. Kruse, a neurosurgeon who himself lost 130 lbs by following an eating plan and monitoring hormones and nutrient levels. There are a few other authors of Leptin Diet type books as well. Dr. Kruse's basic Rx in a nutshell: within 30 minutes of awakening, eat 50 to 75 grams of protein (called a BAB=Big Ass Breakfast). Eat 2 to 3 meals per day, spaced about 5 hours apart. Do not eat within 3 hours of bedtime. No snacking. Sleep 7.5 to 9+ hours per night. Exercise is gentle at first, increasing later as you lose weight and regain leptin sensitivity. The Leptin Reset is P3 friendly, no grain, no legumes, no dairy, no sugar. Just protein, veggies and limited fruit, all based on individual levels of health.
In lab studies, rats who had leptin resistance did not lose weight while on restricted calories, while the leptin sensitive rats would lose. They found that correcting the leptin resistance enabled the fat rats to lose weight, and maintain. Another study showed that subjects who had their leptin levels optimized after weight loss were more successful in keeping the weight off. I'm not going to link to these studies, as the links can be found easy enough through google or in the Leptin Diet thread.
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