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Old 07-27-2012, 04:17 PM   #4
hechicxxrr

Join Date
Oct 2005
Posts
557
Senior Member
Default
I take SAM-e and haven't had any issues. The big thing with SAM-e is to make sure that you take your B vitamins. SAM-e always works better with the B's. Most people notice huge difference with depression within 3 days of starting it. I personally love it Be careful from where you order it because most amounts aren't standardized. Natures Made which you can find in most stores is the most consistent with their formula.
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