As far as I know, no one has ever tested an Ambully. So, one can not claim that they ever had game to lose, or that they are game. Just as most people can't claim their APBT is game. Only one way to know for sure, and in the US, that way is illegal. Now can they all have drive and tenacity? Yes. So, for me, the question is unanswerable, though, the answer is most likely that an Ambully would not be game (as that wasn't what it was bred for or anything like that). However, who would win, doesn't determine who is game anyway.