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SAN FRANCISCO， March 7 (Xinhua) -- Researchers have found a new way to identify the lipids， or fats found in the skin of people who have atopic dermatitis.


The findings were announced in the newly published British Journal of Dermatology.


Researchers have also discovered a link between this debilitating skin problem， altered lipid profiles and some types of bacterial infections such as taphylococcus aureus， or a staph infection.


With the findings， the new therapies will be possible for millions of people with atopic dermatitis， which is one of the most common forms of eczema.


Researchers believe that the staph infections may both lead to atopic dermatitis problems and make people more prone to further infections -- a cycle of skin inflammation that can disrupt the skin microbiome and be one component of this disease that has been so resistant to long-term treatment.


"For the first time we will be able to identify the individual lipids that may be needed to help someone's skin return to health. This may be of value not only to patients with atopic dermatitis or other skin diseases， but even for normal individuals who simply want their skin to be more healthy， well hydrated and resistant to aging，" said Arup Indra， an associate professor in the College of Pharmacy at Oregon State University (OSU) and lead author of the study.


Lipids， or fats， are a vital part of healthy skin， serving almost as a "blanket" to help protect its integrity. As part of the innate immune system， they can also act as a natural barrier to infection; when properly balanced and healthy， they can help prevent skin cancer.


Skin lipids include ceramides， free fatty acids， cholesterol and triglycerides. When these lipids are not available in the right type or amount， skin inflammation can occur.


In atopic dermatitis patients， this can range from mild， intermittent rashes to severe， almost continual skin problems over significant portions of a person's body. Some amount of atopic dermatitis is common in infants， but in some people it's a lifelong issue.


Steroid drugs， either topical or systemic， have been one of the few ways to treat atopic dermatitis， but they have a wide range of side effects that make long-term treatment a concern. Moisturizing creams， lotions， special diets and other approaches have shown limited success.


With the new technology as a result of the study， researchers can identify a person's individual skin lipid profile with some simple tests.


A type of tape has been developed that can pull some lipids off a person's skin， allow testing of them with the use of a mass spectrometer， and have the results compared to the skin lipid profiles of generally healthy patients.


With this information， researchers in the future should be able to determine quite specifically what lipids are deficient， and develop topical compounds to replace them -- either individually， or with compounds that could aid groups of people who share similar lipid profiles.


"These findings about altered lipid profiles and the link to bacterial infections could be a breakthrough to ultimately help many people who struggle with atopic dermatitis and related skin problems，" Indra was quoted as saying in a news release from OSU on Tuesday.


Researchers hope to interrupt the cycle of skin inflammation and staph infections through the use of personalized lipid-replacing compounds， and create a new， promising approach to therapy.


"This has the potential to remove any guess work that might have existed in the past regarding the correct combination of lipids required to improve skin health，" Indra said， "and will help restore to people's skin the right quantity and type of lipids they need."


PARIS Comprar Hombre Nike VaporMax Grises Blancas 849558-004 , July 26 (Xinhua) -- A study presented at the ninth International AIDS Conference on HIV Science in Paris on Tuesday revealed that treatment can ensure zero odds of sexual transmission of the HIV virus.


The large-scale research was led by Austrian experts from the Kirby Institute, following almost 350 homosexual couples with one person HIV positive having treatment.


"If a person is diagnosed and quickly gets on to treatment Comprar Hombre Nike VaporMax Negras Anthracite , then they quickly become non-infectious and that is great news for HIV prevention more broadly, because it's an absolutely key part of us trying to turn this epidemic around and drive infections down Comprar Nike VaporMax Flyknit Negras ," chief investigator Professor Andrew Grulich told Austrian media.


In the study, each couple reported their sexual activity to the research team Comprar Nike VaporMax Off-White , and the HIV negative partners were regularly tested to diagnose any new infections.


The result showed that all the couples had sex almost 17,000 times without condoms over four years Comprar Nike VaporMax CS , and no new infections were reported except three cases affected by sex outside of the relationships.


Current HIV treatment works by suppressing the level of virus, so that immune system damage is halted and even reversed. When treatment is consistently taken Comprar Nike VaporMax Grises , the virus levels will drop so that they become undetectable in the blood.


However, uncertainty remains. Professor Grulich said the general advice is that a person should wait at least three to six months to confirm they are non-infectious by a blood test.


Besides Comprar Nike VaporMax Blancas , an experimental HIV vaccine regimen which was well-tolerated and generated immune responses against HIV in an early-stage clinical trial was presented at the conference on Monday.


The trial called APPROACH involved nearly 400 volunteers in the United States, Rwanda Comprar Nike VaporMax 2018 , Uganda, South Africa and Thailand.


The new vaccine is based on "mosaic" vaccines designed to induce immunological responses against a wide variety of HIV subtypes responsible for HIV infections globally.


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