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Old 12-09-2011, 08:08 PM   #1
Thifiadardivy

Join Date
Nov 2005
Posts
552
Senior Member
Default Probiotics may promote longevity
Unfortunately, this is a pay per view article, but there is growing evidence of the health benefits of probiotics. Jeannine and I recommend this product:

http://www.shareasale.com/r.cfm?b=28...%20Supplements


Volume 77, Issue 4, Pages 469-472 (October 2011)

Probiotics-induced increase of large intestinal luminal polyamine concentration may promote longevity

Mitsuharu Matsumotoa, Shin Kuriharab
published online 11 July 2011.

Abstract
Many mechanisms contribute to senescence, such as telomere shortening in replicative cells, cumulative damage to DNA leading to genomic instability, and oxidative damage to molecules by reactive oxygen species (ROS). These include chronic low-grade inflammation (inflammageing), a major risk factor for ageing and age-related diseases, such as Alzheimer’s disease and type II diabetes. Furthermore, the prevention of inflammageing seems to be one of the most effective approaches to increase longevity. Here, I discuss the rationale and recent evidence for probiotic-induced upregulation of intestinal luminal polyamine (PA) production in the extension of lifespan by preventing inflammageing.

a Dairy Science and Technology Institute, Kyodo Milk Industry Co. Ltd., 20-1 Hirai, Hinode-cho, Nishitama-gun, Tokyo 190-0182, Japan
b Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University Sakyo-ku, Kyoto 606-8502, Japan
Corresponding author. Tel.: +81 42 597 5911; fax: +81 42 597 5910.

PII: S0306-9877(11)00269-6

doi:10.1016/j.mehy.2011.06.011

© 2011 Elsevier Ltd. All rights reserved.
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