Researchers have discovered a new method that tricks ageing stem cells into a rejuvenating mode that could help design youthful patches for damaged hearts and heal them.
According to researchers, the breakthrough may enable scientists to create such life giving patches from a patient’s own stem cells avoiding the threat of rejection. Stem cell therapies involving donated bone marrow stem cells run the risk of patient rejection in a portion of the population.
How did they do this? The Clinical trials of this kind of therapy using elderly patient’s own cells have not been a viable option, since aged cells tend not to function as well as cells from young patients.
They created a “micro-environment” that allows heart tissue to grow, with stem cells donated from elderly patients. The cell cultures are then infused with a combination of growth factors positioned in such a way that the cells are able to be stimulated by these factors.