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United States Pharmacopeia (USP) published the revised mandatory Chapter 41 on balances as well as new updates to the advisory Chapter 1251. With just six months to comply Authentic Hisashi Iwakuma Jersey , METTLER TOLEDO's global weighing standard, GWP, can help pharmaceutical manufacturers and suppliers to meet the new requirements. The new revisions define modified balance test procedures for the US pharmaceutical industry and also apply to companies exporting to the US. With the revised chapters becoming official on 1st December, 2013 Authentic Felix Hernandez Jersey , METTLER TOLEDO is providing a new free interactive on-demand webinar to explain how balance quality management will be affected, focusing on the determination of minimum weight and execution of routine testing.
For a long time balance users and manufacturers argued that balance assessment as per USP's General Chapter 41 ("Balances") was unclear and difficult to comply with. In addition, they frequently commented that General Chapter 1251 ("Weighing on an Analytical Balance") no longer represented state-of-the-art weighing practices. The revisions to both chapters in the Second Supplement to USP 36-NF 31 aim to help US pharmaceutical manufacturers and suppliers ensure accuracy and eliminate costly over-testing. METTLER TOLEDO's Global Weighing Standard: Good Weighing Practice (GWP) can help consumers put the new standards into practice in a structured, effective Authentic Edgar Martinez Jersey , and easy to understand way. Demanding Balance Assessment The new requirements of General Chapter 41 are mandatory. The revised chapter details a relatively demanding balance assessment, outlining accuracy and repeatability tests for calibrated balances used to weigh analytes for quantitative measures. Since accuracy can only be gauged using weights that are at least 5% of an instrument's capacity, test weight selection criteria have also been modified accordingly (weights smaller than 5% cannot assess systematic deviations sufficiently well enough). Achieve Time Savings without Compromising Accuracy General Chapter 1251 provides additional clarification on the new procedures and extends the scope to any balance used for an analytical procedure. It details that balance performance verification should be carried out using a risk-based approach. Very importantly, it is recommended to only weigh net samples which weigh sufficiently more than the minimum weight to account for fluctuations in the balance's performance due to varying influences from the environment and the balance operators. This requirement is clearly applied to the sample weight itself-and not to the tare vessel. Additionally-and perhaps most importantly to pharmaceutical manufacturers-daily testing recommendations have been dropped. This change is expected to provide significant time savings which Authentic Dee Gordon Jersey , if accompanied by weighing accuracy, will offer monetary savings as well. Ensuring Accuracy in the New Environment Although these revisions imply that unnecessary testing must be eliminated to protect manufacturing margins in today's highly competitive pharmaceutical market, they continue to underscore that weighing accuracy is non-negotiable. METTLER TOLEDO's GWP - The Weighing Standard-can help manufacturers implement the new USP regulations. Tailored to each weighing application, GWP Verification is a unique Authentic Carlos Ruiz Jersey , risk-based service that helps eliminate redundant or erroneous testing. Thanks to determining the minimum weight and measurement uncertainty for each and every balance and scale used in the weighing process, manufacturers not only optimize SOPs, ensure consistent product quality and pass air-tight audits, they also avoid potentially costly litigation and fines resulting from a poorly-formulated Ryon Healy Jersey , out-of-specification product. Consistent Quality with GWP Verification With daily testing out of the way, pharmaceutical manufacturers have the opportunity to strengthen their balance testing procedures and create enhanced assurance that their products remain safe, effective, and profitable. GWP Verification's unique Robinson Cano Jersey , systematic guidance can help make weighing consistency-and product quality-part of a pharmaceutical manufacturer's everyday production reality without burdensome over-testing. METTLER TOLEDO's free On-Demand Webinar explaining the implications of the new USP revisions can be viewed at: http:us.mtusenhomeeventswebinarondemandproduct-organizationsgwpInteractive_GWP_USP_Chapters_41_12551?crel=ePR_PP_EN Contact information: Mettler-Toledo International Inc. Im Langacher, Zip Code 8606 Greifensee, Switzerland E-Mail : ePublicRelations@mt Phone : +41-44-944 33 85 Website : www.mt LUSAKA, May 17 (Xinhua) -- The Zambian government on Wednesday said it will continue implementing business reforms in order to attract more investment. Inonge Wina Randy Johnson Jersey , the country's vice president, said the government was collaborating with other stakeholders such as the World Bank and the private sector on implementing business reforms aimed at easing doing business in the country. In remarks delivered in the southern city of Livingstone at the start of the 2017 Ease of Doing Business Initiative Conference, the Zambian vice president said the government has come up with a number of reforms aimed at addressing constraints faced by the private and that it will continue with the reforms, according to state broadcaster Nelson Cruz Jersey , the Zambia National Broadcasting Corporation. Minister of Commerce, Trade and Industry Margaret Mwanakatwe said during the same occasion that the country's global position on the Ease of Doing Business Index was an indication that the country needed to do more to undertake more business reforms. She said the country's overall ranking on the Ease of Doing Business for 2017 stood at 98 out of 190 countries. The country is ranked. 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