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After 11 days of ditzing around with the protocol (not gaining but not loosing, either), my diet buddy telling me I am too "inquisitive" (my word, she used a different phrase) for my own good and just follow protocol, and needing to understand why I can eat much lower-than-normal calories (but still 200-300 more than protocol) and still not loose weight, I started researching the hypothalamus/leptin/insulin issue.
Ran across the following tidbit in this article: http://ajpregu.physiology.org/conten....full.pdf+html >>First, two of the hallmarks in the induction of diet-induced leptin resistance are elevated body weight (primarily fat) levels and increased circulating leptin concentrations. In the current study, after 6 mo of fructose feeding, circulating leptin levels, body weight, and body fat of the fructose-fed group were identical to those of the control group (rats who consumed an equicaloric 60% starch diet). This alone renders the phenomenon a unique form of diet-induced leptin resistance. Second,leptin resistance induced by fructose feeding led to a pronounced susceptibility to increased weight gain on an already potent obesity-inducing 60% HF diet. Third, as the authors note, fructose-induced leptin resistance has the characteristics of a “silent” form of the phenomenon, remaining undetectable (with one exception) by standard measures of food intake, body weight gain, and serum hormone and metabolite levels, until a HF diet is made available to previously fructose-fed rats. |
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